Anderson, only 5-foot-3 (1.61 meters), quit with a shoulder injury after leading Eri Hozumi of Japan 3-2 in the first set at the Gold River Racquet Club in the Sacramento area.
Hozumi's countrywoman Mayo Hibi, seeded seventh, dismissed Jamie Loeb of Ossining, N.Y., 6-2, 6-3.
Hibi, who was born in Japan but grew up in Irvine, Calif., won the 2013 Gold River Challenger at age 17. Loeb, a product of the John McEnroe Tennis Academy in New York, turned pro after winning the NCAA singles title last year as a North Carolina sophomore.
Kristie Ahn, who played No. 2 singles on Stanford's 2013 NCAA championship team, topped Renata Zarazua of Mexico 5-7, 6-3, 6-3.
Second-seeded Grace Min of Boca Raton, Fla., beat Claire Liu, a 16-year-old wild card from Thousand Oaks in the Los Angeles area, 6-4, 6-4.
At Wimbledon this month, Liu reached the girls singles quarterfinals and won the girls doubles title with countrywoman Usue Maitane Arconada.
$50,000 FSP GOLD RIVER WOMEN'S CHALLENGER
In Gold River, Calif.
At Gold River Racquet Club
Final-round qualifyingChanel Simmonds (3), South Africa, def. Caroline Romeo (5), France, 6-4, 6-0.
Alexandra Stevenson, United States, def. Alexandra Sanford, United States, 6-4, 6-4.
Lizette Cabrera, Australia, def. Maegan Manasse, United States, 6-4, 7-6 (7).
Valeria Solovyeva (1), Russia, def. Tori Kinard (8), United States,4-6, 7-5, 6-1.
First roundEri Hozumi, Japan, def. Robin Anderson (4), United States, 2-3, retired.
Mayo Hibi (7), Japan, def. Jamie Loeb, United States, 6-2, 6-3.
Sabina Sharipova (8), Uzbekistan, def. Storm Sanders, Australia, 3-6, 6-1, 6-2.
Grace Min (2), United States,def. Claire Liu, United States,6-4, 6-4.
First roundAn-Sophie Mestach, Belgium, and Tara Moore (1), Great Britain, def. Alexandra Facey and Kat Facey, Cameron Park, Calif., 6-1, 6-4.
Jacqueline Cako, United States, and Jovana Jaksic, Serbia, def. Ashley Mackey, United States, and Karina Kristina Vyrlan, Sacramento, 6-1, 6-3.
Ashley Weinhold and Caitlin Whoriskey (2), United States, def. Greet Minnen and Alison Van Uytvanck, Belgium, 6-4, 6-1.
Jamie Loeb, United States, and Chanel Simmonds (3), South Africa, def. Caroline Dolehide and Sofia Kenin, United States, 6-4, 6-3.
Yuki Kristina Chiang, United States, and Elizaveta Ianchuk, Ukraine, def. Kaitlyn Christian and Sabrina Santamaria, United States, 6-2, 6-7 (3) [10-5].
(Starting at 10 a.m.)
StadiumJovana Jaksic (5), Serbia, vs. Sofia Kenin, United States.
Alison Van Uytvanck (1), Belgium, vs. Caroline Romeo, France (not before 11:30 a.m.).
An-Sophie Mestach (3), Belgium, vs. Cristiana Ferrando, Italy (not before 1 p.m.).
Robin Anderson and Maegan Manasse, United States, vs. Shiho Akita, Japan, and Caroline Romeo, France (not before 2:30 p.m., possible court change).
Isabella Kling, Orangevale, and Laura McGaffigan, Folsom, vs. Freya Christie and Laura Robson (4), Great Britain (not before 4:30 p.m.).
Court 3Priscilla Hon, Australia, vs. Karina Kristina Vyrlan, Sacramento.
Tara Moore (6), Great Britain, vs. Laura Robson, Great Britain (not before 11:30 a.m.).
Michaella Krajicek, Netherlands, vs. Sabrina Santamaria, United States (not before 1 p.m.).
Kristie Ahn and Grace Min, United States, vs. Lizette Cabrera and Priscilla Hon, Australia (not before 2:30 p.m.).
Court 4Greet Minnen, Belgium, vs. Freya Christie, Great Britain.
Alexandra Stevenson, United States, vs. Riko Sawayanagi, Japan (not before 11:30 a.m.).
Chanel Simmonds, South Africa, vs. Valeria Solovyeva, Russia (not before 1 p.m.).
Court 5Lizette Cabrera, Australia, vs. Ellie Halbauer, United States.
Elizaveta Ianchuk, Ukraine, vs. Shiho Akita, Japan (not before 11:30 a.m.).